Perioperative β blockers in patients having non-cardiac surgery: a meta-analysis
نویسندگان
چکیده
Background American College of Cardiology and American Heart Association (ACC/AHA) guidelines on perioperative assessment recommend perioperative β blockers for non-cardiac surgery, although results of some clinical trials seem not to support this recommendation. We aimed to critically review the evidence to assess the use of perioperative β blockers in patients having non-cardiac surgery.
منابع مشابه
The effects of perioperative β-blockers on mortality in patients undergoing non-cardiac surgery in real world: a meta-analysis of cohort studies.
BACKGROUND Despite the fact that recent evidence from meta-analysis of randomized trials indicates an increase in mortality, perioperative treatment with β-blockers is still widely advocated. We therefore performed a meta-analysis of cohort studies to evaluate the effects of perioperative β-blockers on mortality in patients undergoing non-cardiac surgery in the real world scenarios. METHODS W...
متن کاملMeta-analysis of secure randomised controlled trials of β-blockade to prevent perioperative death in non-cardiac surgery
BACKGROUND Current European and American guidelines recommend the perioperative initiation of a course of β-blockers in those at risk of cardiac events undergoing high- or intermediate-risk surgery or vascular surgery. The Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography (DECREASE) family of trials, the bedrock of evidence for this, are no longer secure. We there...
متن کاملHow strong is the evidence for the use of perioperative beta blockers in non-cardiac surgery? Systematic review and meta-analysis of randomised controlled trials.
OBJECTIVE To determine the effect of perioperative beta blocker treatment in patients having non-cardiac surgery. DESIGN Systematic review and meta-analysis. DATA SOURCES Seven search strategies, including searching two bibliographic databases and hand searching seven medical journals. STUDY SELECTION AND OUTCOMES: We included randomised controlled trials that evaluated beta blocker treatme...
متن کاملPerioperative beta blockers in patients having non-cardiac surgery: a meta-analysis.
BACKGROUND American College of Cardiology and American Heart Association (ACC/AHA) guidelines on perioperative assessment recommend perioperative beta blockers for non-cardiac surgery, although results of some clinical trials seem not to support this recommendation. We aimed to critically review the evidence to assess the use of perioperative beta blockers in patients having non-cardiac surgery...
متن کاملSequential analysis shows that β blockade in non-cardiac surgery is ineffective and may even be harmful.
Bolsin and colleagues state that “conclusive evidence has not emerged” on the use of perioperative β blockers. Sequential analysis is a tool for quantifying the amount of information, and it can therefore determine when firm evidence is reached in cumulative meta-analysis. We recently carried out a sequence analysis in which we examined the data from nine “secure” trials (10 529 patients) of pe...
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تاریخ انتشار 2005